tailieunhanh - Báo cáo vật lý: "Surface Engineering of Titania for Excellent Fibroblast 3T3 Cell-Metal Interaction"

Tuyển tập các báo cáo nghiên cứu khoa học trên tạp chí khoa học vật lý quốc tế đề tài: Surface Engineering of Titania for Excellent Fibroblast 3T3 Cell-Metal Interaction | Journal of Physical Science Vol. 20 1 35-47 2009 35 Surface Engineering of Titania for Excellent Fibroblast 3T3 Cell-Metal Interaction Roshasnorlyza Hazan1 Srimala Sreekantan1 Adilah Abdul Khalil2 Ira Maya Sophia Nordin2 and Ishak Mat2 1School of Materials and Mineral Resources Engineering Engineering Campus 14300 Nibong Tebal Pulau Pinang Malaysia 2Advanced Medical and Dental Institute Universiti Sains Malaysia Suite 121 141 Kompleks EUREKA 11800 USM Pulau Pinang Malaysia Corresponding author roshasnorlyza@ Abstract The present study is focussed on clarifying the influence of different surface structures nanotubes thin film and foam of titania TiOf on the cell interactions of fibroblast 3T3 cells. The nanotubes were prepared by an anodisation process thin film by a sol-gel method and foam by the sacrificed polymeric sponge method. Their in vitro bioactivity was investigated by soaking the sample in complete growth medium RPMI-1640 DMEM with 3T3 cells. Field Emission Scanning Electron Microscope FESEM micrograph and optical density results showed that self-arrayed TiO2 nanotubes strongly enhanced cellular activities followed by the foam structure and the thin film. Atomic Force Microscope AFM results provided evidence that the enhanced cell interaction in nanotubes is associated with the roughness of the surface. Keywords surface engineering TiO2 nanotubes TiO2 thin film TiO2 foam cell-metal interaction Abstrak Kajian ini difokuskan untuk menjelaskan kesan struktur permukaan berbeza tiub-nano filem nipis dan busa bagi titania TiO2 ke atas tindak balas sel fibroblas 3T3 . Tiub-nano disediakan melalui proses penganodan filem nipis melalui kaedah solgel manakala busa dengan kaedah pengorbanan busa polimer. Bioaktiviti in vitro dikaji dengan merendam sampel di dalam medium tumbesaran lengkap RPMI-1640 DMEM dengan sel 3T3. Keputusan mikrograf Field Emission Scanning Elektron Microscope FESEM dan ketumpatan optik menunjukkan tiub-nano tersusun sendiri telah .