tailieunhanh - Insulin Action and Its Disturbances in Disease - part 7

Tham chiếu giao thức 5 năm, bao gồm 6 tháng đầu tiên (ngẫu nhiên) thí điểm nghiên cứu, bao gồm chế độ ăn uống điều trị và / hoặc tăng PA hoặc đào tạo với kiểm tra tổng quát hàng năm xét nghiệm OGTT - ăn chay và insulin sau thách thức | Table continued. Reference Objective of study Participant characteristics Nature of intervention Measure of insulin resistance Confounders adjusted for Direction and magnitude of effect 185 Non-randomized controlled trial The study was a prospective study to test the feasibility aspect of long term intervention with an emphasis on life-style changes N m f 222 Age SD BMI years Ethnicity Swedish Caucasians A 5 year protocol including an initial 6 month randomized pilot study consisting of dietary treatment and or increase of PA or training with annual check-ups OGTT - fasting and post-challenge insulin Reduction in 0 40 min increment and 2 h insulin during intervention p in intervention groups but not in control groups. Reduction in 2 h insulin from baseline to 5 year follow-up p for trend in intervention groups p 186 Randomized controlled trial To assess the effect of lifestyle modification on insulin in newly diagnosed type 2 N m f 86 Age 40-64 years BMI Nationality Finnish After 3 months of routine care groups were randomized to either conventional care or diet and exercise for 12 months OGTT - fasting and post-challenge insulin Insulin significantly reduced in the intervention group diabetics 356 PHYSICAL ACTIVITY AND INSULIN RESISTANCE 81 Un-controlled trial 20 week endurance exercise training trial aimed at modifying metabolic parameters in sedentary individuals Randomized controlled trial To assess the combined effects of diet and exercise on insulin resistance N m f 51 46 Age years BMI Ethnicity Caucasian N m f 219 Age 40 years Ethnicity Caucasian The intervention was diet and exercise recommendations specific instructions 3 week for 20 week supervised aerobic exercise training programme 1 year intervention trial involving supervised endurance exercise training 3 week Fasting insulin Stratified by sex No effect of exercise training on insulin levels HOMA Significant reduction in insulin resistance with diet and exercise