tailieunhanh - Báo cáo hóa học: "Coupling of Semiconductor Nanowires with Neurons and Their Interfacial Structure"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Coupling of Semiconductor Nanowires with Neurons and Their Interfacial Structure | Nanoscale Res Lett 2010 5 410-415 DOI s11671-009-9498-0 NANO EXPRESS Coupling of Semiconductor Nanowires with Neurons and Their Interfacial Structure Ki-Young Lee Sojung Shim Il-Soo Kim Hwangyou Oh Sunoh Kim Jae-Pyeong Ahn Seung-Han Park Hyewhon Rhim Heon-Jin Choi Received 26 October 2009 Accepted 16 November 2009 Published online 4 December 2009 The Author s 2009. This article is published with open access at Abstract We report on the compatibility of various nanowires with hippocampal neurons and the structural study of the neuron-nanowire interface. Si Ge SiGe and GaN nanowires are compatible with hippocampal neurons due to their native oxide but ZnO nanowires are toxic to neuron due to a release of Zn ion. The interfaces of fixed Si nanowire and hippocampal neuron cross-sectional samples were prepared by focused ion beam and observed by transmission electron microscopy. The results showed that the processes of neuron were adhered well on the nanowire without cleft. Keywords Nanowires Neurons Coupling Interfaces TEM . Lee S. Shim . Kim H. Oh . Choi Department of Materials Science and Engineering Yonsei University Seoul 120-749 South Korea e-mail hjc@ S. Kim Jeonnam Natural Resources Research Institute Jangheung-Gun Jeollanamdo 529-851 South Korea . Ahn Advanced Analysis Center Korea Institute of Science and Technology Seoul 136-791 South Korea . Park Department of Physics Yonsei University Seoul 120-749 South Korea H. Rhim Center for Chemoinformatics Research Korea Institute of Science and Technology Seoul 136-791 South Korea e-mail hrhim@ Introduction Semiconductor nanowires have high aspect ratio high surface area and single crystallinity and thus are ideal building blocks for many devices on a nanometer scale 1 2 . Among these nanowire-based neuron devices that can monitor or stimulate neurons on a submicron dimension with high sensitivity have been recently noticed for their great potential .