tailieunhanh - báo cáo hóa học: " Correlations among improvements in urgency urinary incontinence, health-related quality of life, and perception of bladder-related problems in incontinent subjects with overactive bladder treated with tolterodine or placebo"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Correlations among improvements in urgency urinary incontinence, health-related quality of life, and perception of bladder-related problems in incontinent subjects with overactive bladder treated with tolterodine or placebo | BioMed Central Health and Quality of Life Outcomes Open Access Correlations among improvements in urgency urinary incontinence health-related quality of life and perception of bladder-related problems in incontinent subjects with overactive bladder treated with tolterodine or placebo Philip EV Van Kerrebroeck 1 Con J Kelleher2 Karin S Coyne3 Zoe Kopp4 Marina Brodsky4 and Joseph T Wang4 Address Department of Urology University Hospital Maastricht Maastricht The Netherlands 2Guys and St. Thomas Hospital NHS Trust London UK 3United Biosource Corporation Center for Health Outcomes Research Bethesda MD USA and 4Pfizer Inc New York NY USA Email Philip EV Van Kerrebroeck - Con J Kelleher - Karin S Coyne - Zoe Kopp - Marina Brodsky - Joseph T Wang - Corresponding author Published 18 February 2009 Received 4 August 2008 Health and Quality of Life Outcomes 2009 7 13 doi 1477-7525-7-13 Accepted 18 February 2009 This article is available from http content 7 1 13 2009 Van Kerrebroeck et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Previous studies demonstrate that tolterodine extended release ER significantly improves urgency urinary incontinence UUI episodes. Instruments that measure patient-reported outcomes PROs provide additional information that is valuable for assessing whether clinical improvements are meaningful to the patient. This study determined the correlation of changes in bladder diary variables and other PROs in subjects with overactive bladder OAB . Methods Subjects with OAB urinary frequency and UUI were treated .