tailieunhanh - báo cáo hóa học: " Utility values for symptomatic non-severe hypoglycaemia elicited from persons with and without diabetes in Canada and the United Kingdom"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Utility values for symptomatic non-severe hypoglycaemia elicited from persons with and without diabetes in Canada and the United Kingdom | Health and Quality of Life BioMed Central Research Utility values for symptomatic non-severe hypoglycaemia elicited from persons with and without diabetes in Canada and the United Kingdom Adrian R Levy 1 2 3 Torsten LU Christensen4 and Jeffrey A Johnson5 Open Access Address 1Oxford Outcomes Ltd. Vancouver BC Canada 2University of British Columbia Vancouver BC Canada 3Centre for Health Evaluation and Outcome Sciences St Paul s Hospital Vancouver BC Canada 4Novo Nordisk A S Denmark and 5School of Public Health University of Alberta Edmonton Alberta Canada Email Adrian R Levy - Torsten LU Christensen - tluc@ Jeffrey A Johnson - Corresponding author Published 29 September 2008 Received 10 March 2008 Accepted 29 September 2008 Health and Quality of Life Outcomes 2008 6 73 doi l477-7525-6-73 This article is available from http content 6 1 73 2008 Levy et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Objective To elicit societal and patient utilities associated with diabetic symptomatic non-severe hypoglycaemia for three health states 1 rare quarterly 2 intermittent monthly 3 and frequent weekly hypoglycaemia episodes. Methods Using validated health states time trade-off utilities were elicited from 51 Canadian respondents with diabetes and 79 respondents in Canada and 75 respondents in the United Kingdom UK without diabetes. Results and discussion Each hypoglycaemic episode was associated with a reduction in utility and persons with diabetes consistently reported slightly higher utility values than respondents without diabetes. The utility for diabetes without hypoglycaemia ranged from to the mean utility for rare .