tailieunhanh - Fatty Liver Disease: NASH and Related Disorders

This chapter introduces the history, definitional and semantic issues, spectrum and general importance of non-alcoholic fatty liver diseases (NAFLD). Nonalcoholic steatohepatitis (NASH) is a form of metabolic liver disease in which fatty change (steatosis) is associated with lobular inflammation, hepatocyte injury and/or hepatic fibrosis. It comprises a pathogenic link in the chain of NAFLD that extends from bland steatosis to some cases of ‘cryptogenic cirrhosis’. | Fatty Liver Disease NASH and Related Disorders Fatty Liver Disease NASH and Related Disorders Edited by Geoffrey C. Farrell Director Storr Liver Unit Westmead Hospital Department of Medicine University of Sydney Sydney NSW 2006 Australia Jacob George Director Clinical Hepatology Storr Liver Unit Westmead Hospital Department of Medicine University of Sydney Sydney NSW 2006 Australia Pauline de la M. Hall University of Cape Town Department of Anatomical Pathology Faculty of Medicine Observatory Cape Town 7925 South Africa Arthur J. McCullough Division of Gastroenterology MetroHealth Medical Center and Schwartz Center for Metabolism and Nutrition Cleveland OH 44102-1998 USA Blackwell .