tailieunhanh - báo cáo hóa học: " Measuring health-related quality of life in tuberculosis: a systemic review - Response"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Measuring health-related quality of life in tuberculosis: a systemic review - Response | Weis and Pasipanodya Health and Quality of Life Outcomes 2010 8 7 http content 8 1 7 HEALTH AND QUALITY of life outcomes LETTER TO THE EDITOR Open Access Measuring health-related quality of life in tuberculosis a systemic review - Response Stephen E Weis1 Jotam G Pasipanodya2 We read with interest the recently published paper by Na Guo et al 1 . The authors identified published studies 2-4 where health-related quality of life instruments were administered to persons with tuberculosis. They then analyzed the health-related quality of life structure validation and health-related quality of life outcomes. The authors conclude that the consensus of the published health-related quality of life literature is that tuberculosis significantly negatively impacts patients quality of life. They further found that even after being microbiologically cured of TB that health-related quality of life remained significantly worse than the general population. We agree with the authors major conclusions that tuberculosis significantly negatively impacts patients quality of life. We also concur that the qualitative evidence they present suggests these impacts persists after microbiological cure of tuberculosis disease. We however did not completely understand their statement in results A validated tuberculosis-specific quality of life instrument was not located . Their methods used to determine if an instrument was validated were not stated. As the authors are aware the ideal methods for validation of health-related quality of life questionnaires are controversial. We recently used the St George s Respiratory Questionnaire to ascertain health-related quality of life in treated TB patients. We used a widely validated generic health-related quality of life instrument and biological measures for construct validity in TB patients. Further most items in the St George s instruments have sound theoretical and practical relevance and have been validated for similar respiratory .