tailieunhanh - báo cáo hóa học: " Can we derive an 'exchange rate' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Can we derive an 'exchange rate' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique | Health and Quality of Life Outcomes BioMed Zentral Research Open Access Can we derive an exchange rate between descriptive and preference-based outcome measures for stroke Results from the transfer to utility TTU technique Duncan Mortimer 1 2 Leonie Segal2 and Jonathan Sturm3 Address 1Centre for Health Economics Monash University Building 75 The Strip Clayton 3800 Australia 2Division of Health Sciences University of South Australia Adelaide 5000 Australia and 3Department of Neurology Gosford Hospital PO Box 361 New South Wales 2250 Australia E-mail Duncan Mortimer - Leonie Segal - Jonathan Sturm - jkmsturm@ Corresponding author Published 17 April 2009 Received 21 November 2007 Health and Quality of Life Outcomes 2009 7 33 doi 186 1477-7525-7-33 Accepted 17 April 2009 This article is available from http content 7 1 33 2009 Mortimer et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Stroke-specific outcome measures and descriptive measures of health-related quality of life HRQoL are unsuitable for informing decision-makers of the broader consequences of increasing or decreasing funding for stroke interventions. The quality-adjusted life year QALY provides a common metric for comparing interventions over multiple dimensions of HRQoL and mortality differentials. There are however many circumstances when - because of timing lack of foresight or cost considerations - only stroke-specific or descriptive measures of health status are available and some indirect means of obtaining QALY-weights becomes necessary. In such circumstances the use of regression-based transformations or mappings can circumvent the failure to .