tailieunhanh - Báo cáo y học: "A transcriptional network associated with natural variation in Drosophila aggressive behavior"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: A transcriptional network associated with natural variation in Drosophila aggressive behavior. | Open Access Researc h A transcriptional network associated with natural variation in Drosophila aggressive behavior Alexis C Edwards Julien F Ayroles Eric A Stone Mary Anna Carbone Richard F Lyman and Trudy FC Mackay Addresses Department of Genetics North Carolina State University Raleigh North Carolina 27695 USA. WM Keck Center for Behavioral Biology North Carolina State University Raleigh North Carolina 27695 USA. Department of Statistics North Carolina State University Raleigh North Carolina 27695 USA. Current address Virginia Institute for Psychiatric and Behavioral Genetics Virginia Commonwealth University Department of Psychiatry Richmond VA 23298-0126 USA. Correspondence Trudy FC Mackay. Email trudy_mackay@ Published 16 July 2009 Genome Biology 2009 10 R76 doi gb-2009- 10-7-r76 The electronic version of this article is the complete one and can be found online at http 2009 10 7 R76 Received 6 March 2009 Revised 3 June 2009 Accepted 16 July 2009 2009 Edwards et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Aggressive behavior is an important component of fitness in most animals. Aggressive behavior is genetically complex with natural variation attributable to multiple segregating loci with allelic effects that are sensitive to the physical and social environment. However we know little about the genes and genetic networks affecting natural variation in aggressive behavior. Populations of Drosophila melanogaster harbor quantitative genetic variation in aggressive behavior providing an excellent model system for dissecting the genetic basis of naturally occurring variation in aggression. Results Correlating variation in transcript abundance with variation in .