tailieunhanh - Báo cáo sinh học: " Correlations of genetic resistance of chickens to Marek’s disease viruses with vaccination protection and in vivo response to"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Correlations of genetic resistance of chickens to Marek’s disease viruses with vaccination protection and in vivo response to | Genet Sei Evol 1990 22 457-469 Elsevier INRA 457 Original article Correlations of genetic resistance of chickens to Marek s disease viruses with vaccination protection and in vivo response to phytohemaglutinin JS Gavora1 JL Spencer2 I Okada3 A A Grander1 with the technical assistance of PS Griffin1 E. Sally 2 1 Agriculture Canada Animal Research Centre Ottawa Ontario Ki A OC6 2 Agriculture Canada Animal Diseases Research Institute Nepean Ontario Canada K2H 8P9 3 Faculty of Applied Biological Science Hiroshima University Department of Animal Science Higashi-Hiroshima Japan Received 6 December 1989 accepted 17 September 1990 Summary - Twenty-three genetic groups of experimental and commercial meat and egg chickens were injected with moderately virulent BC-1 exp 1 or highly virulent RB-1B exp 2 Marek s disease MD virus. Birds of 7 genetic groups were divided into vaccinated and non-vaccinated groups and exposed by contact to the virulent RB-1B virus in exp 3. Response to phytohemaglutinin PHA injected in wing webs was measured in adult birds of all 23 groups exp 4 to assess its relationship to MD resistance. There was a high correlation between resistance of the genetic groups to the two viruses indicating that selection for resistance to one virus would be expected to improve resistance to the other virus. Regression of MD incidence in vaccinated birds on that in non-vaccinated birds resulted in regression coefficients of and for males females and combined sexes respectively indicating that MD incidence increased linearly in vaccinated birds in relation to their genetic susceptibility to MD. Two significant correlations in males suggested that high swelling response to PHA may under some conditions be associated with MD resistance. However the correlation coefficients were inconsistent and it was concluded that swelling response to PHA inoculated in the wing web is not predictive of MD resistance. chicken Marek s disease vaccination .

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