tailieunhanh - Chronic interstitial lung disease in children

The beneficial aspects of stress diminish when it is severe enough to over- whelm a child’s ability to cope effectively. Intensive and prolonged stress can lead to a variety of short- and long-term negative health effects. It can disrupt early brain development and compromise functioning of the nervous and immune systems. In addition, childhood stress can lead to health problems later in life including alcoholism, depression, eating disorders, heart disease, cancer, and other chronic diseases. The purpose of this publication is to summarize the research on childhood stress and its implications for adult health and well-being. Of particular interest is the stress. | 0021-7557 07 83-03 233 Jornal de Pediatria Copyright 2007 by Sociedade Brasileira de Pediatria Original Article Chronic interstitial lung disease in children Maria Aparecida S. S. Paiva 1 Sandra M. M. Amaral2 Abstract Objectives To describe clinical and diagnostic features and the results of therapeutic conduct in a group of pediatric patients with chronic interstitial lung disease. Methods A retrospective study of 25 immunocompetent patients aged 2 months to 17 years with chronic interstitial lung disease admitted to the Pediatric Pulmonary Section Department of Pediatrics Hospital dos Servidores do Estado over a 20-year period 1984-2004 . A routine protocol for persistent chronic pneumonias was used and the patients with interstitial lung disease were selected. Clinical laboratory and imaging data were analyzed. Results Twenty-five patients were diagnosed with chronic interstitial lung disease 13 were aged less than 2 years and 17 were male. Diagnoses were made based on history physical examination and routine tests in one case based on more complex tests in three cases and based on the results of invasive tests in 21 cases 20 by lung biopsy and one by bronchoalveolar lavage . Except for one patient with pulmonary lymphangiectasia the long-term treatment 1 to 7 years consisted of corticosteroid in six cases associated with hydroxychloroquine. Four patients required home oxygen therapy. The authors followed the patients in the outpatient department 6 a 8 visits year . Patient outcome was good 15 regular with mild sequelae 4 and poor with severe sequelae 3 . One patient was lost in the follow-up period and two died. Conclusions Chronic interstitial lung diseases in children are a group of rare pulmonary disorders but a relevant one because of the possible progression to pulmonary fibrosis. Early diagnosis and a long-term specialized treatment and follow-up are important for the patient outcome. Pediatricians should be aware of these diseases because in many cases .