tailieunhanh - Báo cáo sinh học: "Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Tissue distribution of DNA-Hsp65/TDM-loaded PLGA microspheres and uptake by phagocytic cells | Genetic Vaccines and Therapy BioMed Central Research Tissue distribution of DNA-Hsp65 TDM-loaded PLGA microspheres and uptake by phagocytic cells Ana Paula F Trombone1 2 Celio L Silva1 2 Luciana P Almeida1 2 Open Access Rogerio S Rosada1 2 Karla M Lima1 Constance Oliver3 Maria C Jamur3 and Arlete AM Coelho-Castelo 1 2 Address 1Departamento de Bioquímica e Imunologia Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo Av. Bandeirantes 3900 14049-900 Ribeirão Preto SP Brasil 2NPT - Núcleo de Pesquisas em Tuberculose - Departamento de Bioquímica e Imunologia Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo Av. Bandeirantes 3900 14049-900 Ribeirão Preto SP Brasil and 3Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo Av. Bandeirantes 3900 14049-900 Ribeirão Preto SP Brasil Email Ana Paula F Trombone - tromboneapf@ Celio L Silva - clsilva@ Luciana P Almeida - lupreviato@ Rogerio S Rosada - rosada@ Karla M Lima - klima@ Constance Oliver - coliver@ Maria C Jamur - mjamur@ Arlete AM Coelho-Castelo - arlete@ Corresponding author Published 20 September 2007 Received 27 June 2007 rr J n I I r 11- m M- r Accepted 20 September 2007 Genetic Vaccines and Therapy 2007 5 9 doi 186 1479-0556-5-9 This article is available from http content 5 1 9 2007 Trombone et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract This study aimed to demonstrate that microspheres used as delivery vehicle of DNA-Hsp65 TDM plasmid DNA encoding heat shock protein 65 Hsp65 coencapsulated with trehalose dimycolate TDM into .