tailieunhanh - báo cáo hóa học:" Rapid serological detection of autoantibodies associated with Sjögren's syndrome"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Rapid serological detection of autoantibodies associated with Sjögren's syndrome | Journal of Translational Medicine BioMed Central Open Access Rapid serological detection of autoantibodies associated with Sjogren s syndrome Peter D Burbelo 1 2 Kathryn H Ching1 2 Alexandra T Issa1 2 Caroline M Loftus1 2 Yi Li1 2 Minoru Satoh1 2 Westley H Reeves1 2 and Michael J ladarola1 2 Address 1Neurobiology and Pain Therapeutics Section Laboratory of Sensory Biology National Institute of Craniofacial Research National Institutes of Health Bethesda Maryland USA and 2Division of Rheumatology and Clinical Immunology and Center for Autoimmune Diseases University of Florida Gainesville Florida USA Email Peter D Burbelo - burbelop@ Kathryn H Ching - Chingk@ Alexandra T Issa - Caroline M Loftus - Yi Li - liyi@ Minoru Satoh - Westley H Reeves - Michael J Iadarola - miadarola@ Corresponding author Published 24 September 2009 Received 23 July 2009 _ _-mno .A I IO ÍIz-rn roi 1 Accepted 24 September 2009 Journal of Translational Medicine 2009 7 83 doi 1479-5876-7-83 This article is available from http content 7 1 83 2009 Burbelo et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Sjogren s syndrome SjS is a relatively common autoimmune disease characterized by oral and ocular dryness. There is an increasing need for simple sensitive and rapid technologies for the diagnosis of SjS and other autoimmune diseases. Here we investigated whether a quick version of luciferase immunoprecipitation systems QLIPS could be used to produce a rapid specific and quantitative test to detect autoantibodies associated .