tailieunhanh - báo cáo hóa học:" Clinical values of multiple Epstein-Barr virus (EBV) serological biomarkers detected by xMAP technology"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Clinical values of multiple Epstein-Barr virus (EBV) serological biomarkers detected by xMAP technology | Journal of Translational Medicine BioMed Central Open Access Clinical values of multiple Epstein-Barr virus EBV serological biomarkers detected by xMAP technology Ai-Di Gu11 2 Li-Xia Lu13 Yan-Bo Xie1 2 Li-Zhen Chen1 2 Qi-Sheng Feng1 2 Tiebang Kang1 2 Wei-Hua Jia1 2 and Yi-Xin Zeng 1 2 Address 1State Key Laboratory of Oncology in Southern China Guangzhou PR China 2Department of Experimental Research Sun Yat-sen University Cancer Center Guangzhou PR China and 3Department of Radiotherapy Sun Yat-sen University Cancer Center Guangzhou PR China Email Ai-Di Gu - topgad@ Li-Xia Lu - lisa2101@ Yan-Bo Xie - ybxie05@ Li- Zhen Chen - clz5312@ Qi-Sheng Feng - fqsh@ Tiebang Kang - kangtb@ Wei- Hua Jia - jiaweih@ Yi-Xin Zeng - zengyix@ Corresponding author fEqual contributors Published 23 August 2009 Received 23 June 2009 _ -T_-mno IIOZIUTO rov 7T Accepted 23 August 2009 Journal of Translational Medicine 2009 7 73 doi 1479-5876-7-73 This article is available from http content 7 1 73 2009 Gu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Serological examination of Epstein-Barr virus EBV antibodies has been performed for screening nasopharyngeal carcinoma NPC and other EBV-associated diseases. Methods By using xMAP technology we examined immunoglobulin Ig A antibodies against Epstein-Barr virus EBV VCA-gpI25 pI8 and IgA IgG against EA-D EBNAI and gp78 in populations with distinct diseases or with different genetic or geographic background. Sera from Cantonese NPC patients n 547 and healthy controls n 542 90 members of high-risk NPC families and 52 non-endemic healthy .