tailieunhanh - DNA REPAIR AND HUMAN HEALTH

Desmoplastic melanoma (DM) is an unusual, non-pigmented, sclerosing variant of spindle cell malignant melanoma that can range in appearance from sarcomatoid to scar-like lesion. Cytomorphologic features described on FNA include a moderate cellularity with pleomorphic spindle cells occurring singly and in small aggregates. The spindle cells exhibit plump nuclei with deep grooves and folds, coarse and clumped chromatin, and inconspicuous to multiple, prominent nucleoli, along with naked spindly nuclei. Intranuclear cytoplasmic inclusions are rare. Generally, cytoplasm is scanty to moderate in amount with a fine wispy character, clinging to the nuclear poles | DNA REPAIR AND HUMAN HEALTH Edited by Sonya Vengrova DNA Repair and Human Health Edited by Sonya Vengrova Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Alenka Urbancic Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat First published October 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ DNA Repair and Human Health Edited by Sonya Vengrova p. cm. ISBN 978-953-307-612-6 ikrrr iJ OPEN ACCESS INI Cvn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .