tailieunhanh - Báo cáo hóa học: " An exploratory investigation of the influence of publication on translational medicine research"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: An exploratory investigation of the influence of publication on translational medicine research | Douet et al. Journal of Translational Medicine 2010 8 62 http content 8 1 62 JOURNAL OF TRANSLATIONAL MEDICINE COMMENTARY Open Access Arlexploratory investigation of the influence of publication on translational medicine research Lisa J Douet Danielle Preedy Vaughan Thomas and Ian A Cree Abstract Background Changes in clinical practice are brought about by the weight of clinical evidence for and against an intervention. Clinical evidence of efficacy relies on the dissemination of research results usually by publication in medical journals which is often seen as a pre-requisite for progression of an intervention through further clinical trials or implementation studies. How far has research progressed along the translational pathway We undertook an exploratory exercise to determine where basic and translational medical research is currently published. Original research articles 329 in total published in high impact general and specialist medical journals were classified into different stages of research within the translational medicine pathway. Where is translational research published The general medical journals had the broadest spread of published research over the translational pathway. The specialist journals tended to be positioned to disseminate the research findings of early stage translational research from basic science results through to early stages of clinical testing. Conclusion It is not possible for one journal to satisfy all the needs of the reader and the author along the translational medicine pathway. For an intervention to progress along the translational pathway background information should be readily accessible in the article. This pathway is currently being actively managed by the funding agencies but the next challenge is to ensure the pathway operates efficiently and does not allow promising innovations to languish and to provide a smoother transition for interventions to reach the clinic in a quicker .