tailieunhanh - Báo cáo y học: "Fly’s time."

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Fly’s time. | Comment Fly s time Gregory A Petsko Address Rosenstiel Basic Medical Sciences Research Center Brandeis University Waltham MA 02454-9110 USA. Email petsko@ Published 29 September 2006 Genome Biology 2006 7 115 doi gb-2006-7-9-ll5 The electronic version of this article is the complete one and can be found online at http 2006 7 9 ll5 2006 BioMed Central Ltd Genome sequences are coming so thick and fast these days that it s easy to forget when any new one guaranteed a cover article in Nature or Science - and occasionally as in the case of the human genome in both. I used to do a column about each new eukaryotic sequence as soon as it came out I haven t felt the need to do that in quite a while. Soon there will be hundreds of bacterial genomes sequenced and dozens of eukaryotes so I guess a certain jaded attitude is understandable. Still it wasn t that long ago that any new one especially from an important model organism was considered so important that sometimes there were races between competing scientific teams to produce them. Of all these races those between teams from the public and private sector were the fiercest involved the most colorful characters and raised the most compelling issues. We remember the epic contest between Francis Collins government-funded group and the rival band from Craig Venter s Celera Corporation to sequence the human genome which led to a brokered announcement of a tie heralded by pictures of the team leaders posing uneasily with one another and President Clinton. We tend to forget however that these same battle-lines were drawn earlier and not over the genome of Homo sapiens or any other mammal. They were drawn over the humble fruit fly Drosophila melanogaster. It is this struggle between well if not exactly God and mammon then at least public mammon and private mammon to sequence the fly genome that is the subject of Michael Ashburner s new book Won for All How the Drosophila Genome Was Sequenced