tailieunhanh - Báo cáo y học: "The role of transposable element clusters in genome evolution and loss of synteny in the rice blast fungus Magnaporthe oryzae"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: The role of transposable element clusters in genome evolution and loss of synteny in the rice blast fungus Magnaporthe oryzae. | Research Open Access The role of transposable element clusters in genome evolution and loss of synteny in the rice blast fungus Magnaporthe oryzae Michael R Thon Huaqin Pan Stephen Diener John Papalas Audrey Taro Thomas K MitchelT and Ralph A Dean Addresses Department of Plant Pathology and Microbiology Texas A M University College Station TX 77843 USA. ỶCenter for Integrated Fungal Research North Carolina State University Raleigh NC 27695 USA. Correspondence Michael RThon. Email mthon@ Published 28 February 2006 Genome Biology 2006 7 R16 doi 186 gb-2006-7-2-r16 The electronic version of this article is the complete one and can be found online at http 2006 7 2 R16 Received 24 October 2005 Revised 16 January 2006 Accepted 31 January 2006 2006 Thon et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Transposable elements are abundant in the genomes of many filamentous fungi and have been implicated as major contributors to genome rearrangements and as sources of genetic variation. Analyses of fungal genomes have also revealed that transposable elements are largely confined to distinct clusters within the genome. Their impact on fungal genome evolution is not well understood. Using the recently available genome sequence of the plant pathogenic fungus Magnaporthe oryzae combined with additional bacterial artificial chromosome clone sequences we performed a detailed analysis of the distribution of transposable elements syntenic blocks and other features of chromosome 7. Results We found significant levels of conserved synteny between chromosome 7 and the genomes of other filamentous fungi despite more than 200 million years of divergent evolution. Transposable elements are .