tailieunhanh - Báo cáo y học: "Intron gain and loss in segmentally duplicated genes in rice"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Intron gain and loss in segmentally duplicated genes in rice. | Research Open Access Intron gain and loss in segmentally duplicated genes in rice Haining Lin Wei Zhu Joana C Silva Xun Gu and C Robin Buell Addresses The Institute for Genomic Research Medical Center Drive Rockville MD 20850 USA. ỶDepartment of Genetics Development and Cell Biology Center for Bioinformatics and Biological Statistics Iowa State University Ames IA 50011 USA. Correspondence C Robin Buell. Email rbuell@ Published 23 May 2006 Genome Biology 2006 7 R4I doi I86 gb-2006-7-5-r4I The electronic version of this article is the complete one and can be found online at http 2006 7 5 R4I Received 30 January 2006 Revised 2I March 2006 Accepted 24 April 2006 2006 Lin et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Introns are under less selection pressure than exons and consequently intronic sequences have a higher rate of gain and loss than exons. In a number of plant species a large portion of the genome has been segmentally duplicated giving rise to a large set of duplicated genes. The recent completion of the rice genome in which segmental duplication has been documented has allowed us to investigate intron evolution within rice a diploid monocotyledonous species. Results Analysis of segmental duplication in rice revealed that I59 Mb of the 37I Mb genome and 2I 570 of the 43 719 non-transposable element-related genes were contained within a duplicated region. In these duplicated regions 3 I0I collinear paired genes were present. Using this set of segmentally duplicated genes we investigated intron evolution from full-length cDNA-supported non-transposable element-related gene models of rice. Using gene pairs that have an ortholog in the dicotyledonous model .