tailieunhanh - Báo cáo y học: "New developments in developmental biology"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: New developments in developmental biology. | Meeting report New developments in developmental biology David AF Loebel Samara L Lewis Renuka S Rao and Leisha D Nolen Address Embryology Unit Children s Medical Research Institute Westmead NSW 2145 Australia. Correspondence David AF Loebel. E-mail dloebel@ Published 23 December 2005 Genome Biology 2005 6 364 doi gb-2005-6-l3-364 The electronic version of this article is the complete one and can be found online at http 2005 6 13 364 2005 BioMed Central Ltd A report on the 15th International Society of Developmental Biologists Congress Sydney Australia 3-7 September 2005. With the theme From egg to adult constructing the complexity of life the recent meeting of the International Society of Developmental Biologists ISDB in Sydney showcased recent progress in answering a broad range of questions on how the body of a multicellular organism is put together and how differences in body patterns evolve. This was the first ISDB congress since the publication of the initial sequence of the mouse genome in 2002 and there is no doubt that genome sequencing and the ability to study the expression of several thousand genes at once has facilitated progress in understanding how genes work to build an embryo. In his opening plenary lecture however Nobel laureate Sydney Brenner The Molecular Sciences Institute Berkeley USA warned that too much emphasis is placed on studying gene function. Brenner said we should thank the people who sequenced the genomes and tell them to go away and cautioned against high-throughput low-output research. He argued that rather than taking the bottom-up approach of studying individual gene function we should study the middle level the cell. In his view we need to know how many different cell types there are in the finished product and then we can start to understand how they got there. Cell lineages and differentiation Focusing on the earliest cell lineages Janet Rossant Samuel Lunenfeld Research Institute .