tailieunhanh - HEALTH   MANAGEMENT –  DIFFERENT APPROACHES AND SOLUTIONS  

However, there are patients with two negative biopsies who continue with a high suspicion of cancer, with a persistently elevated PSA or pre-malignant histology report such as prostate intraepithelial neoplasia grade 3 or atypical microacinar proliferation. The evidence suggests that cancers diagnosed with the third or fourth biopsy are those of low grade and volume (Djavan, 2001). The key question is how often is it justified to re-biopsy the patient that perhaps does not have a cancer that is life threatening. The diagnosis of a prostate cancer not clinically significant implies an overdiagnosis and over-treatment. However, there are no predictive factors, clinical or laboratorial that help to. | HEALTH MANAGEMENT -DIFFERENT APPROACHES AND SOLUTIONS Edited by Krzysztof Smigórski Health Management - Different Approaches and Solutions Edited by Krzysztof Smigórski Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Iva Simcic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team Image Copyright Denis Vrublevski 2011. Used under license from First published November 2011 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Health Management - Different Approaches and Solutions .

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