tailieunhanh - Báo cáo y học: " The diversity of bacterial pathogenicity mechanisms"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The diversity of bacterial pathogenicity mechanisms. | Meeting report The diversity of bacterial pathogenicity mechanisms Eugene Rosenberg Address Department of Molecular Microbiology and Biotechnology Tel Aviv University 69978 Ramat Aviv Israel. E-mail eros@ Published 8 April 2005 Genome Biology 2005 6 320 doi gb-2005-6-5-320 The electronic version of this article is the complete one and can be found online at http 2005 6 5 320 2005 BioMed Central Ltd A report on the international conference Molecular basis of bacterial pathogenesis sponsored by the Federation of European Microbiological Societies FEMS and the Israel Center for the Study of Emerging Diseases Ein Gedi Israel 23-27 January 2005. One of the remarkable features of the recent FEMS meeting on the molecular basis of bacterial pathogenesis was the novel ways in which genome sequences are now being used to study bacterial pathogens. In the 10 years since the first complete sequence of the genome of a pathogenic bacterium - that of Haemophilus influenzae - was published the genomes of almost all the major human pathogens have been sequenced. The first and most obvious use of these data was comparative genome analysis in order to understand what distinguishes pathogenic from nonpathogenic strains. While this approach continues to be useful for discovering new genes that cause disease virulence genes which are possible targets for new antibacterial drugs and clusters of virulence genes pathogenicity islands in the genome and for providing clues to how pathogens have evolved several new approaches to using genome data were presented at the meeting. These include the development of new vaccines reverse vaccinology uncovering new biosynthetic pathways studying how bacteria adapt rapidly to new environments and the beginning of a comprehensive comparison of genomics and proteomics. The genetics of pathogenicity Virulent strains of Escherichia coli can be divided into two classes those that cause intestinal disease and those .

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