tailieunhanh - Báo cáo y học: "The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The Adult Mouse Anatomical Dictionary: a tool for annotating and integrating data. | Software Open Access The Adult Mouse Anatomical Dictionary a tool for annotating and integrating data Terry F Hayamizu Mary Mangan John P Corradi James A Kadin and Martin Ringwald Addresses The Jackson Laboratory 600 Main Street Bar Harbor ME 04609 USA. ỶCurrent address OpenHelix 65 Main Street Somerville MA 02145 USA. Bristol-Myers Squibb Pharmaceutical Research Institute 5 Research Parkway Wallingford CT 06492 USA. Correspondence Martin Ringwald. E-mail ringwald@ Published 15 February 2005 Genome Biology 2005 6 R29 The electronic version of this article is the complete one and can be found online at http 2005 6 3 R29 Received 31 August 2004 Revised 8 November 2004 Accepted I I January 2005 2005 Hayamizu et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract We have developed an ontology to provide standardized nomenclature for anatomical terms in the postnatal mouse. The Adult Mouse Anatomical Dictionary is structured as a directed acyclic graph and is organized hierarchically both spatially and functionally. The ontology will be used to annotate and integrate different types of data pertinent to anatomy such as gene expression patterns and phenotype information which will contribute to an integrated description of biological phenomena in the mouse. S Rationale An important role for biological databases is the integration of different types of data. Ontologies aim to overcome the semantic differences encountered in data collection and representation providing common terminology in order to facilitate this integration. An anatomy ontology is a structured vocabulary of anatomical entities in which the terms have unique identities and relate to each other in meaningful ways. For