tailieunhanh - Báo cáo y học: "The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information. | Method Open Access The Mammalian Phenotype Ontology as a tool for annotating analyzing and comparing phenotypic information Cynthia L Smith Carroll-Ann W Goldsmith and Janan T Eppig Addresses The Jackson Laboratory 600 Main Street Bar Harbor ME 04609 USA. Massachusetts College of Pharmacy and Health Sciences School of Pharmacy Manchester 1260 Elm Street Manchester NH 03101 USA. Correspondence Janan T Eppig. E-mail jte@ Published 15 December 2004 Genome Biology 2004 6 R7 The electronic version of this article is the complete one and can be found online at http 2004 6 1 R7 Received 8 September 2004 Revised 15 November 2004 Accepted 17 November 2004 2004 Smith et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The Mammalian Phenotype MP Ontology enables robust annotation of mammalian phenotypes in the context of mutations quantitative trait loci and strains that are used as models of human biology and disease. The MP Ontology supports different levels and richness of phenotypic knowledge and flexible annotations to individual genotypes. It continues to develop dynamically via collaborative input from research groups mutagenesis consortia and biological domain experts. The MP Ontology is currently used by the Mouse Genome Database and Rat Genome Database to represent phenotypic data. Background Mammalian phenotypes are complex and the term itself is imprecise. Generally we use the word phenotype in referring to the appearance or manifestation of a set of traits in an individual that result from the combined action and interaction of genotype and environment. Because mouse is the premier model organism for the study of human biology and disease the goal of comparative phenotyping

TÀI LIỆU LIÊN QUAN
TỪ KHÓA LIÊN QUAN
crossorigin="anonymous">
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.