tailieunhanh - Báo cáo y học: "The Sequence Ontology: a tool for the unification of genome annotations"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The Sequence Ontology: a tool for the unification of genome annotations. | Method Open Access The Sequence Ontology a tool for the unification of genome annotations Karen Eilbeck Suzanna E Lewis Christopher J Mungall Mark Yandell Lincoln Stein Richard Durbin and Michael Ashburner Addresses Department of Molecular and Cellular Biology Life Sciences Addition University of California Berkeley CA 94729-3200 USA. Howard Hughes Memorial Institute Department of Molecular and Cellular Biology Life Sciences Addition University of California Berkeley CA 94729-3200 USA. Cold Spring Harbor Laboratory 1 Bungtown Road Cold Spring Harbor New York 11724 USA. Sanger Institute Wellcome Trust Genome Campus Hinxton Cambridgeshire CB10 1SA UK. Department of Genetics University of Cambridge Downing Street Cambridge CB2 3EH UK. Correspondence MichaelAshburner. E-mail ma11@ Published 29 April 2005 Genome Biology 2005 6 R44 doi 186 gb-2005-6-5-r44 The electronic version of this article is the complete one and can be found online at http 2005 6 5 R44 Received 4 October 2004 Revised 1 February 2005 Accepted 30 March 2005 2005 Eilbeck et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The Sequence Ontology SO is a structured controlled vocabulary for the parts of a genomic annotation. SO provides a common set of terms and definitions that will facilitate the exchange analysis and management of genomic data. Because SO treats part-whole relationships rigorously data described with it can become substrates for automated reasoning and instances of sequence features described by the SO can be subjected to a group of logical operations termed extensional mereology operators. Background Why a sequence ontology is needed Genomic annotations are the focal point of sequencing .

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