tailieunhanh - Báo cáo sinh học: "Detection of quantitative trait loci for reproduction and production traits in Large White and French Landrace pig populations"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Detection of quantitative trait loci for reproduction and production traits in Large White and French Landrace pig populations | Genet. Sel. Evol. 40 2008 61-78 INRA EDP Sciences 2008 DOI gse 2007035 Available online at Original article Detection of quantitative trait loci for reproduction and production traits in Large White and French Landrace pig populations Open Access publication Thierry Tribout1 Nathalie IANNUCCELLI2 Tom DRUET1 Hélène Gilbert1 Juliette RIQUET2 Ronan Gueblez3 Marie-José MERCAT3 Jean-Pierre BIDANEL1 Denis MILAN2 Pascale Le Roy4 1INRA UR337 Station de génétique quantitative et appliquée 78352 Jouy-en-Josas France 2INRA UR444 Laboratoire de génétique cellulaire 31326 Castanet-Tolosan France 3IFIP Institut du Porc La Motte au Vicomte BP 35104 35651 Le Rheu Cedex France 4INRA UMR598 Génétique animale 35042 Rennes France Received 17 January 2007 accepted 31 July 2007 Abstract - A genome-wide scan was performed in Large White and French Landrace pig populations in order to identify QTL affecting reproduction and production traits. The experiment was based on a granddaughter design including five Large White and three French Landrace half-sib families identified in the French porcine national database. A total of 239 animals 166 sons and 73 daughters of the eight male founders distributed in eight families were geno-typed for 144 microsatellite markers. The design included 51 262 animals recorded for production traits and 53 205 litter size records were considered. Three production and three reproduction traits were analysed average backfat thickness US_M and live weight LWGT at the end of the on-farm test age of candidates adjusted at 100 kg live weight total number of piglets born per litter and numbers of stillborn STILLp and born alive LIVp piglets per litter. Ten QTL with medium to large effects were detected at a chromosome-wide significance level of 5 affecting traits US_M on SSC2 SSC3 and SSC17 LWGT on SSC4 STILLp on SSC6 SSC11 and SSC14 and LIVp on SSC7 SSC16 and SSC18 . The number of heterozygous male founders varied from 1 to 3 depending .