tailieunhanh - Báo cáo sinh học: " An algorithm for efficient constrained mate selection Brian P Kinghorn"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: An algorithm for efficient constrained mate selection Brian P Kinghorn | Kinghorn Genetics Selection Evolution 2011 43 4 http content 43 1 4 RESEARCH GSE Ge n et i cs Selection Evolution Open Access An algorithm for efficient constrained mate selection Brian P Kinghorn Abstract Background Mate selection can be used as a framework to balance key technical cost and logistical issues while implementing a breeding program at a tactical level. The resulting mating lists accommodate optimal contributions of parents to future generations in conjunction with other factors such as progeny inbreeding connection between herds use of reproductive technologies management of the genetic distribution of nominated traits and management of allele genotype frequencies for nominated QTL markers. Methods This paper describes a mate selection algorithm that is widely used and presents an extension that makes it possible to apply constraints on certain matings as dictated through a group mating permission matrix. Results This full algorithm leads to simpler applications and to computing speed for the scenario tested which is several hundred times faster than the previous strategy of penalising solutions that break constraints. Conclusions The much higher speed of the method presented here extends the use of mate selection and enables implementation in relatively large programs across breeding units. Background Mate selection is the process of choosing mating pairs or groups . simultaneous selection and mate allocation of animals entering a breeding program 1 . This can be carried out before mating to make decisions for the active mating group but it can also be carried out at other stages. Mate selection can cover almost all of the decisions to be made in a selection program including culling among juveniles decisions on semen and embryo collection or purchase migration of breeding stock active matings and backup matings. It can also be used to set up investment matings . assortative matings to invest in increased genetic variation .