tailieunhanh - Báo cáo sinh học: " Haplotype inference in crossbred populations without pedigree information"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Haplotype inference in crossbred populations without pedigree information | Genetics Selection Evolution BioMed Central Research Haplotype inference in crossbred populations without pedigree information Albart Coster 1 Henri CM Heuven1 2 Rohan L Fernando3 and Jack CM Dekkers3 Address 1Animal Breeding and Genomics Centre Wageningen University Wageningen The Netherlands 2Clinical Sciences of Companion Animals Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands and 3Department of Animal Science Center for Integrated Animal Genomics Iowa State University Ames Iowa USA Email Albart Coster - Henri CM Heuven - Rohan L Fernando - rohan@ Jack CM Dekkers - jdekkers@ Corresponding author Open Access Published II August 2009 Received 3 February 2009 Genetics Selection Evolution 2009 41 40 doi 1297-9686-41 -40 Accepted 1 1 August 2009 This article is available from http content 41 1 40 2009 Coster et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Current methods for haplotype inference without pedigree information assume random mating populations. In animal and plant breeding however mating is often not random. A particular form of nonrandom mating occurs when parental individuals of opposite sex originate from distinct populations. In animal breeding this is called crossbreeding and hybridization in plant breeding. In these situations association between marker and putative gene alleles might differ between the founding populations and origin of alleles should be accounted for in studies which estimate breeding values with marker data. The sequence of alleles from one parent constitutes one .