tailieunhanh - Báo cáo sinh học: " History of Lipizzan horse maternal lines as revealed by mtDNA analysis"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: History of Lipizzan horse maternal lines as revealed by mtDNA analysis | Genet. Sel. Evol. 34 2002 635-648 635 INRA EDP Sciences 2002 DOI gse 2002028 Original article History of Lipizzan horse maternal lines as revealed by mtDNA analysis Tatjana KAVARa Gottfried BREMb Franc HABEa Johann SõLKNERc Peter Dovca a Department of Animal Science Biotechnical Faculty University of Ljubljana Groblje 3 1230 Domzale Slovenia b Ludwig Boltzmann-Institut fur immuno- zyto- molekulargenetische Forschung Veterinarmedizinishe Universitat Wien Veterinarplatz 1 1210 Wien Austria c Department of Livestock Science University of Agricultural Sciences Gregor Mendel Strasse 33 1180 Wien Austria Received 26 November 2001 accepted 25 March 2002 Abstract - Sequencing of the mtDNA control region 385 or 695 bp of 212 Lipizzans from eight studs revealed 37 haplotypes. Distribution of haplotypes among studs was biased including many private haplotypes but only one haplotype was present in all the studs. According to historical data numerous Lipizzan maternal lines originating from founder mares of different breeds have been established during the breed s history so the broad genetic base of the Lipizzan maternal lines was expected. A comparison of Lipizzan sequences with 136 sequences of domestic- and wild-horses from GenBank showed a clustering of Lipizzan haplotypes in the majority of haplotype subgroups present in other domestic horses. We assume that haplotypes identical to haplotypes of early domesticated horses can be found in several Lipizzan maternal lines as well as in other breeds. Therefore domestic horses could arise either from a single large population or from several populations provided there were strong migrations during the early phase after domestication. A comparison of Lipizzan haplotypes with 56 maternal lines according to the pedigrees showed a disagreement of biological parentage with pedigree data for at least 11 of the Lipizzans. A distribution of haplotype-frequencies was unequal -26 mainly due to pedigree errors and haplotype .