tailieunhanh - MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION

In a certain sense, the field of drug metabolism (DM) is standing still. More specifically, the basic experiment of drug metabolism (., administering a new drug to an animal or human and determining the structures, amounts, and disposition of the metabolites) has changed very little over a period of decades. Remarkably, the experimental design and resulting data set from a typical absorption, distribution, metabolism, and excretion (ADME) study conducted today would be instantly recognized and understood by DM scientists from 50 years ago. This is not the case with most other disciplines in the life sciences | MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION WILEY SERIES ON PHARMACEUTICAL SCIENCE AND BIOTECHNOLOGY PRACTICES APPLICATIONS AND METHODS Series Editor Mike S. Lee Milestone Development Services Mike S. Lee Integrated Strategies for Drug Discovery Using Mass Spectrometry Birendra Pramanik Mike S. Lee and Guodong Chen Characterization of Impurities and Degradants Using Mass Spectrometry Mike S. Lee and Mingshe Zhu Mass Spectrometry in Drug Metabolism and Disposition Basic Principles and Applications MASS SPECTROMETRY IN DRUG METABOLISM AND DISPOSITION Basic Principles and Applications Edited by Mike S. Lee Milestone Development Services Mingshe Zhu Bristol-Myers Squibb @ WILEY A JOHN WILEY SONS INC. .