tailieunhanh - báo cáo khoa học: " Development of a novel data mining tool to find cis-elements in rice gene promoter regions"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Development of a novel data mining tool to find cis-elements in rice gene promoter regions | BMC Plant Biology BioMed Central Software Open Access Development of a novel data mining tool to find c s-elements in rice gene promoter regions Koji Doi1 Aeni Hosaka1 Toshifumi Nagata1 Kouji Satoh1 Kohji Suzuki2 Ramil Mauleon3 Michael J Mendoza3 Richard Bruskiewich3 and Shoshi Kikuchi 1 Address 1National Institute of Agrobiological Sciences 2-1-2 Kannondai Tsukuba Ibaraki 305-8602 Japan 2Hitachi Software Engineering Japan Co. Ltd. 6-81 Onoe-cho Naka-ku Yokohama 231-0015 Japan and international Rice Research Institute DAPO 7777 Metro Manila Philippines Email Koji Doi - kdoi@ Aeni Hosaka - aeni@ Toshifumi Nagata - nagatat@ Kouji Satoh - ksatoh@ Kohji Suzuki - ksuzuki@ Ramil Mauleon - rpmauleon@ Michael J Mendoza - mvm4p@ Richard Bruskiewich - Shoshi Kikuchi - skikuchi@ Corresponding author Published 27 February 2008 Received 8 May 2007 BMC Plant Biology 2008 8 20 doi 1471-2229-8-20 Accepted 27 February 2008 This article is available from http 1471-2229 8 20 2008 Doi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Information on more than 35 000 full-length Oryza sativa cDNAs together with associated microarray gene expression data collected under various treatment conditions has made it feasible to identify motifs that are conserved in gene promoters and may act as cis-regulatory elements with key roles under the various conditions. Results We have developed a novel tool that searches for cis-element candidates in the upstream downstream or coding regions of differentially regulated genes. The tool first lists cis-element candidates by .

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