tailieunhanh - báo cáo khoa học: " Evidence for the rapid expansion of microRNA-mediated regulation in early land plant evolution"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evidence for the rapid expansion of microRNA-mediated regulation in early land plant evolution | BMC Plant Biology BioMed Central Research article Open Access Evidence for the rapid expansion of microRNA-mediated regulation in early land plant evolution Isam Fattash1 Bjorn VoK2 Ralf Reski1 Wolfgang R Hess2 and Wolfgang Frank 1 Address 1Faculty of Biology Institute of Biology II Plant Biotechnology University of Freiburg Schaenzlestrasse 1 79104 Freiburg Germany and 2Faculty of Biology Institute of Biology II Experimental Bioinformatics University of Freiburg Schaenzlestrasse 1 79104 Freiburg Germany Email Isam Fattash - Bjorn VoK - Ralf Reski - Wolfgang R Hess - Wolfgang Frank - Corresponding author Published 14 March 2007 Received 22 February 2007 BMC Plant Biology 2007 7 13 doi l47l-2229-7-l3 Accepted I4 March 2007 This article is available from http l47l-2229 7 l 3 2007 Fattash et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background MicroRNAs miRNAs are regulatory RNA molecules that are specified by their mode of action the structure of primary transcripts and their typical size of 20-24 nucleotides. Frequently not only single miRNAs but whole families of closely related miRNAs have been found in animals and plants. Some families are widely conserved among different plant taxa. Hence it is evident that these conserved miRNAs are of ancient origin and indicate essential functions that have been preserved over long evolutionary time scales. In contrast other miRNAs seem to be species-specific and consequently must possess very distinct functions. Thus the analysis of an .