tailieunhanh - Báo cáo y học: "Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium. | Research Open Access Exploring systemic RNA interference in insects a genome-wide survey for RNAi genes in Tribolium Yoshinori Tomoyasu Ỷ Sherry C Miller Shuichiro Tomita Michael Schoppmeier Daniela Grossmann and Gregor Bucher Addresses Division of Biology Kansas State University Manhattan Kansas 66506 USA. fK-State Arthropod Genomics Center Kansas State University Manhattan Kansas 66506 USA. Insect Genome Research Unit National Institute of Agrobiological Sciences 1-2 Owashi Tsukuba Ibaraki 305-8634 Japan. Universitat Erlangen Institut fur Biologie Abteilung fur Entwicklungsbiologie Staudtstr. D-91058 Erlangen Germany. Johann-Friedrich-Blumenbach-Institut fur Zoologie und Anthropologie Georg-August-Universitat Gottingen Abteilung Entwicklungsbiologie Justus-von-Liebig-Weg 37077 Gottingen Germany. Correspondence Yoshinori Tomoyasu. Email tomoyasu@ Published 17 January 2008 Received 20 July 2007 Genome Biology 2008 9 R10 doi 186 gb-2008-9-1-r10 ReVLSeLl3 ov . 007 gy g Accepted 17 January 2008 The electronic version of this article is the complete one and can be found online at http 2008 9 1 R10 2008 Tomoyasu et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background RNA interference RNAi is a highly conserved cellular mechanism. In some organisms such as Caenorhabditis elegans the RNAi response can be transmitted systemically. Some insects also exhibit a systemic RNAi response. However Drosophila the leading insect model organism does not show a robust systemic RNAi response necessitating another model system to study the molecular mechanism of systemic RNAi in insects. Results We used Tribolium which exhibits robust systemic RNAi as an alternative model system. We have .