tailieunhanh - PROTEIN PHOSPHORYLATION IN HUMAN HEALTH

Protein phosphorylation is a reversible posttranslational modification catalyzed by protein kinases and reversely by protein phosphatases. There are about 500 protein kinases and 25-30 phosphatases in human genome. Each kinase and phosphatase targets multiple substrates. Thus, protein phosphorylation is a most versatile signaling regulatory mechanism and constitutes a most complicated signaling network in living organisms. In fact, protein phosphorylation governs all aspects of physiological and pathological processes in human health | PROTEIN PHOSPHORYLATION IN HUMAN HEALTH Edited by Cai Huang Protein Phosphorylation in Human Health http 2944 Edited by Cai Huang Contributors Elena Tchevkina Andrey Komelkov Andrei V. Budanov Bjorn Stork Sebastian Alers Antje S. Loffler Sebastian Wesselborg Jing Pu Pingsheng Liu Olga Calvo Alicia García Martin Lutzelberger Norbert F. Kaufer Katrin Deinhardt Freddy Jeanneteau Andres Joaquin Lopez-Contreras Oscar Fernandez-Capetillo Dmytro Pavlov John G. Mielke Nina Kurrle Bincy John Melanie Meister Ritva Tikkanen Masataka Oda Masahiro Nagahama Keiko Kobayashi Jun Sakurai Yamuna D. Gandaharen Rachel S. Welt David Kostyal Sydney Welt Roberta Fraschini Erica Raspelli Corinne Cassani C. Frazer . Young Shuishu Wang Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Vedran Greblo Typesetting InTech Prepress Novi Sad Cover InTech Design Team First published .