tailieunhanh - Báo cáo khoa học: " A rat model of picornavirus-induced airway infection and inflammation"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A rat model of picornavirus-induced airway infection and inflammation | Virology Journal BioMed Central Research A rat model of picornavirus-induced airway infection and inflammation Louis A Rosenthal 1 2 Svetlana P Amineva2 3 Renee J Szakaly1 2 Robert F Lemanske Jr1 2 3 James E Gern2 3 and Ronald L Sorkness1 2 3 4 Open Access Address Department of Medicine University of Wisconsin School of Medicine and Public Health 600 Highland Avenue Madison WI 53792 USA 2Morris Institute for Respiratory Research University of Wisconsin School of Medicine and Public Health 600 Highland Avenue Madison WI 53792 USA 3Department of Pediatrics University of Wisconsin School of Medicine and Public Health 600 Highland Avenue Madison WI 53792 USA and 4School of Pharmacy University of Wisconsin-Madison Madison WI 53705 USA Email Louis A Rosenthal - lar@ Svetlana P Amineva - spamineva@ Renee J Szakaly - szakaly@ Robert F Lemanske - rfl@ James E Gern - gern@ Ronald L Sorkness - rlsorkness@ Corresponding author Published II August 2009 Received 18 March 2009 Accepted 1 1 August 2009 Virology Journal 2009 6 122 doi 1743-422X-6-122 This article is available from http content 6 1 122 2009 Rosenthal et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Infection of the lower airways by rhinovirus a member of the picornavirus family is an important cause of wheezing illnesses in infants and plays an important role in the pathogenesis of rhinovirus-induced asthma exacerbations. Given the absence of natural rhinovirus infections in rodents we investigated whether an attenuated form of mengovirus a picornavirus whose .