tailieunhanh - Báo cáo khoa học:" In vitro host range, multiplication and virion forms of recombinant viruses obtained from co-infection in vitro with a vaccinia-vectored influenza vaccine and a naturally occurring cowpox virus isolate"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: In vitro host range, multiplication and virion forms of recombinant viruses obtained from co-infection in vitro with a vaccinia-vectored influenza vaccine and a naturally occurring cowpox virus isolate | Virology Journal BioMed Central Open Access In vitro host range multiplication and virion forms of recombinant viruses obtained from co-infection in vitro with a vaccinia-vectored influenza vaccine and a naturally occurring cowpox virus isolate Malachy Ifeanyi Okeke1 2 0ivind Nilssen3 4 Ugo Moens1 Morten Tryland5 and Terje Traavik 2 6 Address Department of Microbiology and Virology Faculty of Medicine University of Tromso N-9037 Tromso Norway 2Gen0k-Centre for Biosafety Tromso Science Park N-9294 Tromso Norway 3Department of Medical Genetics Institute of Clinical Medicine University of Tromso N-9037 Tromso Norway 4University Hospital of North-Norway N-9038 Tromso Norway 5Department of Food Safety and Infection Biology The Norwegian School of Veterinary Science N-9010 Tromso Norway and institute of Pharmacy Faculty of Medicine University of Tromso N-9037 Tromso Norway Email Malachy Ifeanyi Okeke - 0ivind Nilssen - Ugo Moens - Morten Tryland - Terje Traavik - terjet@ Corresponding author Published 12 May 2009 Received 2 April 2009 Accepted 12 May 2009 Virology Journal 2009 6 55 doi l 743-422X-6-55 This article is available from http content 6 1 55 2009 Okeke et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Poxvirus-vectored vaccines against infectious diseases and cancer are currently under development. We hypothesized that the extensive use of poxvirus-vectored vaccine in future might result in co-infection and recombination between the vaccine virus and naturally occurring poxviruses resulting in hybrid viruses with unpredictable characteristics. Previously we confirmed that .