tailieunhanh - Báo cáo khoa học: " Towards a sane and rational approach to management of Influenza H1N1 2009"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Towards a sane and rational approach to management of Influenza H1N1 2009 | Virology Journal BioMed Central Commentary Towards a sane and rational approach to management of Influenza H1N1 2009 William R Gallaher Open Access Address Department of Microbiology Immunology and Parasitology Louisiana State University Health Sciences Center 1901 Perdido Street New Orleans Louisiana 70112 USA Email William R Gallaher - billg35445@ Published 7 May 2009 Received 7 May 2009 Accepted 7 May 2009 Virology Journal 2009 6 51 doi l 743-422X-6-51 This article is available from http content 6 1 51 2009 Gallaher licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Beginning in March 2009 an outbreak of influenza in North America was found to be caused by a new strain of influenza virus designated Influenza H1N1 2009 which is a reassortant of swine avian and human influenza viruses. Over a thousand total cases were identified with the first month chiefly in the United States and Mexico but also involving several European countries. Actions concerning Influenza H1N1 2009 need to be based on fact and science following recommendations of public health officials and not fueled by political legal or other interests. Every influenza outbreak or pandemic is unique so the facts of each one must be studied before an appropriate response can be developed. While reports are preliminary through the first 4 weeks of the outbreak it does not appear to be severe either in terms of the attack rate in communities or in the virulence of the virus itself. However there are significant changes in both the hemagglutinin and neuraminidase proteins of the new virus and of the amino acid sequence from prior H1N1 isolates in 2008 and the current vaccine. Such a degree of change qualifies as an