tailieunhanh - Báo cáo y học: " Genetic predisposition to chikungunya – a blood group study in chikungunya affected families"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Genetic predisposition to chikungunya – a blood group study in chikungunya affected families | Virology Journal BioMed Central Open Access Short report Genetic predisposition to chikungunya - a blood group study in chikungunya affected families Sudarsanareddy Lokireddy1 Vemula Sarojamma2 and Vadde Ramakrishna 1 Address Department of Biotechnology Sri Krishnadevaraya University Anantapur - 515 003 India and 2Department of Community Medicine Government Medical College Anantapur - 518001. India Email Sudarsanareddy Lokireddy - l_suda2003@ Vemula Sarojamma - vemula_saroja@ Vadde Ramakrishna - vrkrishna70@ Corresponding author Published 16 June 2009 Received 23 April 2009 Accepted 16 June 2009 Virology Journal 2009 6 77 doi 1743-422X-6-77 This article is available from http content 6 1 77 2009 Lokireddy et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Chikungunya fever is a viral disease transmitted to humans by the bite of CHIKV virus infected Aedes mosquitoes. During monsoon outbreak of chikungunya fever we carried out the genetic predisposition to chikungunya in disease affected 100 families by doing blood group ABO tests by focusing on individuals who were likely to have a risk of chikungunya and identified the blood group involved in susceptibility resistance to chikungunya. In the present study based on blood group antigens the individuals were kept in four groups - A 108 B 98 AB 20 and O 243 . The result obtained was showed all Rh positive blood group individuals are susceptible to chikungunya fever. Among ABO group the blood group O ve individuals are more susceptible to chikungunya than other blood groups. No blood group with Rh negative was affected with chikungunya it indicates Rh -ve more resistance to chikungunya. Chikungunya an .