tailieunhanh - Báo cáo khoa học: "PreS1 epitope recognition in newborns after vaccination with the third-generation Sci-B-Vac™ vaccine and their relation to the antibody response to hepatitis B surface antigen"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: PreS1 epitope recognition in newborns after vaccination with the third-generation Sci-B-Vac™ vaccine and their relation to the antibody response to hepatitis B surface antigen | BioMed Central Virology Journal Research PreSl epitope recognition in newborns after vaccination with the third-generation Sci-B-Vac vaccine and their relation to the antibody response to hepatitis B surface antigen Ulla B Hellstrom2 5 Kazimierz Madalinski3 6 and Staffan PE Sylvan 1 4 Address Department of Communicable Disease Control and Prevention Uppsala County Council Sweden 2Department of Communicable Disease Control and Prevention Stockholm County Council Sweden 3National Institute of Public Health - National Institute of Hygiene Warsaw Poland 4Department of Medical Sciences Uppsala University Sweden 5The Karolinska Institute Department of Medicine Infectious Disease Unit Karolinska University Hospital Sweden and 6Child Health Memorial Institute Warsaw Poland Email Ulla B Hellstrom - Kazimierz Madalinski - kmadalinski@ Staffan PE Sylvan - Corresponding author Open Access Published 20 January 2009 Received 24 November 2008 Accepted 20 January 2009 Virology Journal 2009 6 7 doi 1743-422X-6-7 This article is available from http content 6 1 7 2009 Hellstrom et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Sci-B-Vac is a recombinant hepatitis B vaccine derived from a mammalian cell line and containing hepatitis B surface antigen HBsAg as well as preSI and preS2 antigens. Few studies have been performed on the antibody responses to preS1 in relation to the antibody to hepatitis B surface antigen anti-HBs response during immunisation of healthy children with preS-containing vaccines. Results In this study 28 healthy newborns were .