tailieunhanh - Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report"

CTuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: hallenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report | Virology Journal BioMed Central Open Access Case Report Challenging complications of treatment - human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin s disease a case report Martin Bommer 1 Sandra Pauls2 and Jochen Greiner1 Address Department of Internal Medicine III - Hematology Oncology University of Ulm Ulm Germany and 2Department of Diagnostic and Interventional Radiology University of Ulm Ulm Germany Email Martin Bommer - Sandra Pauls - Jochen Greiner - Corresponding author Published 20 July 2009 Received 18 April 2009 Virology Journal 2009 6 111 doi 1743-422X-6-11 1 Accepted 20 July 2009 This article is available from http content 6 1 1 11 2009 Bommer et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Reactivation of human herpesvirus 6 HHV-6 occurs frequently in patients after allogeneic stem cell transplantation and is associated with bone-marrow suppression enteritis pneumonitis pericarditis and also encephalitis. After autologous stem cell transplantation or intensive polychemotherapy HHV-6 reactivation is rarely reported. Case report This case demonstrates a severe symptomatic HHV-6 infection with encephalitis and pneumonitis after autologous stem cell transplantation of a patient with relapsed Hodgkin s disease. Conclusion Careful diagnostic work up in patients with severe complications after autologous stem cell transplantation is mandatory to identify uncommon infections. Background Viruses that belong to the herpes group such as HSV1 2 HHV6 and CMV are known to reactivate after intensive .