tailieunhanh - Báo cáo y học: "Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài:Drawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 species. | Research Open Access Drawing the tree of eukaryotic life based on the analysis of 2 269 manually annotated myosins from 328 species Florian Odronitz and Martin Kollmar Address Department of NMR-based Structural Biology Max-Planck-Institute for Biophysical Chemistry Am Fassberg 37077 Goettingen Germany. Correspondence Martin Kollmar. Email mako@ Published 18 September 2007 Genome Biology 2007 8 R196 doi gb-2007-8-9-rl 96 The electronic version of this article is the complete one and can be found online at http 2007 8 9 R196 Received 6 March 2007 Revised 17 September 2007 Accepted 18 September 2007 2007 Odronitz and Kollmar licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The evolutionary history of organisms is expressed in phylogenetic trees. The most widely used phylogenetic trees describing the evolution of all organisms have been constructed based on single-gene phylogenies that however often produce conflicting results. Incongruence between phylogenetic trees can result from the violation of the orthology assumption and stochastic and systematic errors. Results Here we have reconstructed the tree of eukaryotic life based on the analysis of 2 269 myosin motor domains from 328 organisms. All sequences were manually annotated and verified and were grouped into 35 myosin classes of which 16 have not been proposed previously. The resultant phylogenetic tree confirms some accepted relationships of major taxa and resolves disputed and preliminary classifications. We place the Viridiplantae after the separation of Euglenozoa Alveolata and Stramenopiles we suggest a monophyletic origin of Entamoebidae Acanthamoebidae and Dictyosteliida and provide evidence for the .