tailieunhanh - Báo cáo y học: "Computational and transcriptional evidence for microRNAs in the honey bee genome"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Computational and transcriptional evidence for microRNAs in the honey bee genome. | Open Access Research Computational and transcriptional evidence for microRNAs in the honey bee genome Daniel B Weaver Juan M Anzola Jay D Evans Jeffrey G Reid Justin T Reese Kevin L Childs Evgeny M Zdobnov Manoj P Samanta Jonathan Miller and Christine G Elsik Addresses Bee Power LP Lynn Grove Road 16481 CR 319 Navasota TX 77868 USA. Department of Animal Science Texas A M University College Station Texas 77843 USA. Bee Research Laboratory USDA-ARS BARC-E Beltsville MD USA. WM Keck Center for Interdisciplinary BioScience Training Houston TX 77005 USA. European Molecular Biology Laboratory Meyerhofstr. Heidelberg Germany. Systemix Institute Los Altos CA 94024 USA. Department of Biochemistry Baylor College of Medicine Houston TX 77030 USA. The Institute for Genome Research Rockville MD 20850 USA. Department of Genetic Medicine and Development University of Geneva Medical School CMU rue Michel-Servet 1 1211 Geneva 4 Switzerland. These authors contributed equally to this work. Correspondence Christine G Elsik. Email c-elsik@ Published I June 2007 Genome Biology 2007 8 R97 doi 186 gb-2007-8-6-r97 The electronic version of this article is the complete one and can be found online at http 2007 8 6 R97 Received 11 August 2006 Revised 13 December 2006 Accepted 1 June 2007 2007 Weaver et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Non-coding microRNAs miRNAs are key regulators of gene expression in eukaryotes. Insect miRNAs help regulate the levels of proteins involved with development metabolism and other life history traits. The recently sequenced honey bee genome provides an opportunity to detect novel miRNAs in both this species and others and to begin to infer the roles of