tailieunhanh - Báo cáo khoa học: " The Asia 2 specific signal peptide region and other domains in fusion protein genes characterized Asia 1 and Asia 2 canine distemper viruses"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The Asia 2 specific signal peptide region and other domains in fusion protein genes characterized Asia 1 and Asia 2 canine distemper viruses | Virology Journal BioMed Central Open Access The Asia 2 specific signal peptide region and other domains in fusion protein genes characterized Asia I and Asia 2 canine distemper viruses Serageldeen Sultan 1 Nataya Charoenvisal2 Nguyen Thi Lan2 3 Ryoji Yamaguchi2 Ken Maeda1 and Kazushige Kai 1 Address Department of Veterinary Microbiology Faculty of Agriculture Yamaguchi University Yamaguchi 753-8515 Japan 2Department of Veterinary Pathology Faculty of Agriculture University of Miyazaki Miyazaki 889-2192 Japan and 3Department of Veterinary Pathology Faculty of Veterinary Medicine Hanoi University of Agriculture Trau Quy-Gia Lam-Ha Noi Vietnam Email Serageldeen Sultan - seaas@ Nataya Charoenvisal - a0d402u@ Nguyen Thi Lan - a0d402u@ Ryoji Yamaguchi - a0d402u@ Ken Maeda - kmaeda@ Kazushige Kai - kzkai@ Corresponding author Published 6 October 2009 Received 5 August 2009 Accepted 6 October 2009 Virology Journal 2009 6 157 doi 1743-422X-6-157 This article is available from http content 6 1 157 2009 Sultan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although the presence of Asia 2 group of canine distemper virus CDV was known by the sequencing and phylogenetic analysis of hemagglutinin H gene the fusion F protein gene sequence of Asia 2 group had not been identified. So the sequence analysis of F gene was carried out to elucidate the genotypic varaitons among Asian isolates. Results The phylogenetic analysis of F and H gene sequences from fourteen CDV isolates obtained from diseased dogs in Japan and Thailand indicated that the F genes had a new initiation codon and extra 27 .