tailieunhanh - Báo cáo y học: "Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury. | Elseviers et al. Critical Care 2010 14 R221 http content 14 6 R221 KS CRITICAL CARE RESEARCH Open Access Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury K irMoim IO l i Plco iorc1 2 DmKarf I I 2n dor Kliof iOf i3 Prir I Ir icfc4 I I l Ì2 Itar in5 Diorro rÌTỉmTỉc6 Monique M Elseviels nobelt L Lins Patlicia Van del Niepen Elic Hoste Maiiu L Malblain Pielle Ddmdb Jacques Devriendt7 for the SHARF investigators Abstract Introduction Outcome studies in patients with acute kidney injuly AKI have focused on differences between modalities of renal replacement therapy RRT . The outcome of conselvative treatment howevel has nevel been compared with RRT. Methods Nine Belgian intensive care units ICUs included all adult patients consecutively admitted with selum creatinine 2 mg dl. Included treatment options were conselvative treatment and intelmittent ol continuous RRT. Disease severity was detelmined using the Stuivenbelg Hospital Acute Renal Failure SHARF score. Outcome palametels studied were mortality hospital length of stay and lenal lecovely at hospital dischalge. Results Out of 1 303 included patients 650 required RRT 58 intelmittent 42 continuous RRT . Overall results showed a highel mortality 43 velsus 58 as well as a longel ICU and hospital stay in RRT patients compared to conselvative treatment. Using the SHARF score fol adjustment of disease severity an increased risk of death fol RRT compared to conselvative treatment of RR 95 CI to was found. Additional collection fol othel severity palametels Acute Physiology And Chlonic Health Evaluation II APACHE II Sequential Olgan Failure Assessment SOFA age type of AKI and clinical conditions confilmed the highel mortality in the RRT gloup. Conclusions The SHARF study showed that the highel mortality expected in AKI patients receiving RRT velsus conselvative treatment can not only be explained by a highel disease severity in .