tailieunhanh - Báo cáo y học: " Association of ABO blood groups with Chikungunya virus Short report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Association of ABO blood groups with Chikungunya virus Short report | Kumar et al. Virology Journal 2010 7 140 http content 7 1 140 VIROLOGY JOURNAL SHORT REPORT Open Access Association of ABO blood groups with Chikungunya virus Naresh CVM Kumar 1 Mahathi Nadimpalli1 Vishnu R Vardhan2 and Sai DVR Gopal 1 Abstract Chikungunya virus CHIKV an emerging arboviral infection of public health concern belongs to the genus Alphavirus family Togaviridae. Blood group antigens are generally known to act as receptors for various etiological agents. The studies defining the relationship between blood groups and CHIKV is limited and hence it is necessary to study these parameters in detail. In the present study 1500 subjects were enrolled and demographic data Age Gender Blood group CHIKV infection status and CHIKV infection confirmation mode was collected from them. The risk of acquiring CHIKV disease and its association with factors such as blood group age and gender was analyzed statistically. The data of this study showed a possible association between blood group age and gender of the study population with CHIKV infection. It is observed that CHIKV infections were higher in individuals with Rh positive blood group when compared to their Rh negative infections were found to be higher in Rh positive individuals of AB and A blood groups than that of Rh negative counterparts. Results also indicated that infections were higher in adults belonging to the age group 30 years and also higher in males as compared to females enrolled in this study. These data present further evidence for the association of the blood groups age and gender to susceptibility to CHIKV infection. Further studies are needed to confirm these findings. This is the second study showing the possible association of blood groups with chikungunya. Findings Chikungunya virus CHIKV belonging to the genus Alphavirus family Togaviridae is transmitted by Aedes mosquitoes Ae. aegyptii and Ae. albopictus Ae. albopic-tus played a pivotal role in .