tailieunhanh - Báo cáo y học: "Prevalence of various Human Papillomavirus (HPV) genotypes among women who subjected to routine Pap smear test in Bushehr city (South west of Iran)2008-2009"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Prevalence of various Human Papillomavirus (HPV) genotypes among women who subjected to routine Pap smear test in Bushehr city (South west of Iran)2008-2009 | Zandi et al. Virology Journal 2010 7 65 http content 7 1 65 VIROLOGY JOURNAL RESEARCH Open Access Prevalence of various Human Papillomavirus HPV genotypes among women who subjected to routine Pap smear test in Bushehr city South west of Iran 2o08-2009 Keivan Zandi1 Seyed Sajjad Eghbali1 Rasool Hamkar2 Shahnaz Ahmadi1 Elissa ramedani1 Iman Deilami1 Heidar Aziz Nejad1 Fatemeh Farshadpour1 Zahra Rastian1 Abstract Background Some genotypes of human papillomaviruses can infect the genital tract and they are important infectious agents which their oncogenicity is regardable. Thus the aim of this study was to determine the prevalence of various genital human papillomaviruses HPV among women being subjected to routine pap smear test in Bushehr city of Iran. Results Based on the collected data 11 samples were detected positive for HPV DNA and 189 samples out of 200 samples were detected negative for HPV DNA. Meanwhile 4 2 samples detected positive for HPV DNA by PCR were detected positive for HPV by pap smear test as well. On the other hand 5 samples which were detected positive for HPV by pap smear test didn t have HPV DNA after being tested by PCR method. Among the 11 positive samples 7 samples were identified as HPV-16 3 samples were HPV-18 and one was HPV-53. Conclusion Regarding the prevalence of highly carcinogen genotypes of HPV in our study determination of genital HPV prevalence among the normal population of women of Bushehr city is recommended. Background Worldwide cervical cancer is the second most common cancer affecting women. Nowadays screening programs have reduced the mortality and morbidity of this disease but 500 000 new cases of invasive cancer of the cervix are still diagnosed annually. Epidemiological and molecular studies have demonstrated that certain types of human Papillomaviruses Highly carcinogen genotypes are the major cause of most cases of cervical cancer 1 . Human papillomaviruses HPVs belong to .