tailieunhanh - Epithelial ovarian cancer: A national clinical guideline

Since it was not considered feasible or cost-effective to offer treatment at every facility offering screening, women were referred to the district hospital for further management after a positive screening test. Although many experts consider it to be safe and appropriate to provide treatment simply on the basis of VIA or VILI, 11,12,13 even though the tests identify some women as being at risk when they do not actually have a lesion that needs treatment, the WKCCPP project was designed to test the value of triage using tests likely to be feasible for district hospitals. . | Scottish Intercollegiate Guidelines Network Epithelial ovarian cancer A national clinical guideline 1 2 3 4 5 6 7 8 9 10 11 12 Introduction Screening and the role of prophylactic oophorectomy Diagnosis Surgical management Chemotherapy Follow up Clinical trials Management of malignant bowel obstruction in relapsed disease Specialist palliative care Information for patients Implementation Development of the guideline Annexes References 1 3 6 8 13 18 19 20 22 23 25 26 29 33 October 2003 COPIES OF ALL SIGN GUIDELINES ARE AVAILABLE BY CALLING 0131 247 3664 OR ONLINE AT KEY TO EVIDENCE STATEMENTS AND GRADES OF RECOMMENDATIONS LEVELS OF EVIDENCE 1 High quality meta-analyses systematic reviews of randomised controlled trials RCTs or RCTs with a very low risk of bias 1 Well conducted meta-analyses systematic reviews of RCTs or RCTs with a low risk of bias 1 - Meta-analyses systematic reviews of RCTs or RCTs with a high risk of bias 2 High quality systematic reviews of case control or cohort studies High quality case control or cohort studies with a very low risk of confounding or bias and a high probability that the relationship is causal 2 Well conducted case control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal 2 - Case control or cohort studies with a high risk of confounding or bias and a significant risk that the relationship is not causal 3 Non-analytic studies . case reports case series 4 Expert opinion GRADES OF RECOMMENDATION Note The grade of recommendation relates to the strength of the evidence on which the recommendation is based. It does not reflect the clinical importance of the recommendation. A B c D At least one meta-analysis systematic review of RCTs or RCT rated as 1 and directly applicable to the target population or A body of evidence consisting principally of studies rated as 1 directly applicable to the target population and demonstrating overall consistency of .