tailieunhanh - báo cáo khoa học: " Phylogenetic analysis, subcellular localization, and expression patterns of RPD3/HDA1 family histone deacetylases in plants"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Phylogenetic analysis, subcellular localization, and expression patterns of RPD3/HDA1 family histone deacetylases in plants | BMC Plant Biology BioMed Central Open Access Research article Phylogenetic analysis subcellular localization and expression patterns of RPD3 HDA1 family histone deacetylases in plants Malona V Alinsug Chun-Wei Yu and Keqiang Wu Address Institute of Plant Biology College of Life Science National Taiwan University Taipei Taiwan Email Malona V Alinsug - malinsug@ Chun-Wei Yu - wayneyu2@ Keqiang Wu - kewu@ Corresponding author Published 28 March 2009 Received 26 November 2008 BMC Plant Biology 2009 9 37 doi 1471-2229-9-37 Accepted 28 March 2009 This article is available from http 1471-2229 9 37 2009 Alinsug et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although histone deacetylases from model organisms have been previously identified there is no clear basis for the classification of histone deacetylases under the RPD3 HDA1 superfamily particularly on plants. Thus this study aims to reconstruct a phylogenetic tree to determine evolutionary relationships between RPD3 HDA1 histone deacetylases from six different plants representing dicots with Arabidopsis thaliana Populus trichocarpa and Pinus taeda monocots with Oryza sativa and Zea mays and the lower plants with Physcomitrella patens. Results Sixty two histone deacetylases of RPD3 HDA1 family from the six plant species were phylogenetically analyzed to determine corresponding orthologues. Three clusters were formed separating Class I Class II and Class IV. We have confirmed lower and higher plant orthologues for AtHDA8 and AtHDA14 classifying both genes as Class II histone deacetylases in addition to AtHDA5 AtHDA15 and AtHDA18. Since Class II histone deacetylases in other eukaryotes have .