tailieunhanh - Chapter 085. Neoplasms of the Lung (Part 10)

Staging of Small Cell Lung Cancer Pretreatment staging for patients with SCLC includes the initial general lung cancer evaluation with chest and abdominal CT scans (because of the high frequency of hepatic and adrenal involvement) as well as fiberoptic bronchoscopy with washings and biopsies to determine the tumor extent before therapy; brain CT scan (10% of patients have metastases); and radionuclide scans (bone) if symptoms or other findings suggest disease involvement in these areas. Bone marrow biopsies and aspirations are rarely performed given the low incidence of isolated bone marrow metastases. Chest and abdominal CT scans are very useful. | Chapter 085. Neoplasms of the Lung Part 10 Staging of Small Cell Lung Cancer Pretreatment staging for patients with SCLC includes the initial general lung cancer evaluation with chest and abdominal CT scans because of the high frequency of hepatic and adrenal involvement as well as fiberoptic bronchoscopy with washings and biopsies to determine the tumor extent before therapy brain CT scan 10 of patients have metastases and radionuclide scans bone if symptoms or other findings suggest disease involvement in these areas. Bone marrow biopsies and aspirations are rarely performed given the low incidence of isolated bone marrow metastases. Chest and abdominal CT scans are very useful to evaluate and follow tumor response to therapy and chest CT scans are helpful in planning chest radiotherapy ports. If signs or symptoms of spinal cord compression or leptomeningitis develop at any time in lung cancer patients with disease of any histologic type a spinal CT scan or MRI scan and examination of the cerebrospinal fluid cytology are performed. If malignant cells are detected radiotherapy to the site of compression and intrathecal chemotherapy usually with methotrexate are given. In addition a brain CT or MRI scan is performed to search for brain metastases which often are associated with spinal cord or leptomeningeal metastases. Resectability and Operability In patients with NSCLC the following are major contraindications to curative surgery or radiotherapy alone extrathoracic metastases superior vena cava syndrome vocal cord and in most cases phrenic nerve paralysis malignant pleural effusion cardiac tamponade tumor within 2 cm of the carina not curable by surgery but potentially curable by radiotherapy metastasis to the contralateral lung bilateral endobronchial tumor potentially curable by radiotherapy metastasis to the supraclavicular lymph nodes contralateral mediastinal node metastases potentially curable by radiotherapy and involvement of the main pulmonary artery. .

• Y học thường thức
• Neoplasms of the Lung
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• Harrisons Internal Medicine
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• Harrisons Internal Medicine
• BMC Cancer
• Bone metastases
• Stereotactic radiotherapy
• Neoplasm metastasis
• Lung neoplasms
• Prostatic neoplasms
• Breast neoplasms
• Multivariate analysis
• Bone neoplasms
• Orthopedic surgery
• Lung cancer
• Atlas of pulmonary cytopathology
• Benign lung neoplasms
• Malignant lung neoplasms
• Unusual and metastatic lesions
• Metastatic lesions
• Colorectal neoplasms
• Molecular targeted therapy
• Molecular diagnostics
• Chest radiology
• Upper lung disease
• Peripheral lung disease
• Unilateral hyperlucent hemithorax
• Congenital lung disease
• BMC Pulmonary Medicine
• Diagnostic yields
• Transbronchial lung biopsy
• Radial probe endobronchial ultrasound
• Specific therapeutic interventions
• Multivariate logistic regression model
• Factors significantly