tailieunhanh - báo cáo khoa học:" Psychometric characteristics of the short form 36 health survey and functional assessment of chronic illness Therapy-Fatigue subscale for patients with ankylosing spondylitis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Psychometric characteristics of the short form 36 health survey and functional assessment of chronic illness Therapy-Fatigue subscale for patients with ankylosing spondylitis | Revicki et al. Health and Quality of Life Outcomes 2011 9 36 http content 9 1 36 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Psychometric characteristics of the short form 36 health survey and functional assessment of chronic illness Therapy-Fatigue subscale for patients with ankylosing spondylitis Dennis A Revicki1 Anne M Rentz1 Michelle P Luo2 and Robert L Wong3 Abstract Background We evaluated the psychometric characteristics of the Short Form 36 SF-36 Health Survey and the Functional Assessment of Chronic Illness Therapy FACIT -Fatigue subscale in patients with ankylosing spondylitis AS . Methods We analyzed clinical and patient-reported outcome PRO data collected during 12-week double-blind placebo-controlled periods of two randomized controlled trials comparing adalimumab and placebo for the treatment of active AS. The Bath Ankylosing Spondylitis Disease Activity Index Bath Ankylosing Spondylitis Functional Index and other clinical measures were collected during the clinical trial. We evaluated internal consistency reliability construct validity and responsiveness to change for the SF-36 and FACIT-Fatigue. Results The SF-36 Cronbach alpha and FACIT-Fatigue Cronbach alpha both had good internal consistency reliability. At baseline SF-36 and FACIT-Fatigue scores correlated significantly with Ankylosing Spondylitis Quality of Life scores r to and r respectively all p . SF-36 scores varied by indicators of clinical severity with greater impairment observed for more severe degrees of clinical activity all p . FACIT-Fatigue scores correlated significantly with SF-36 scores r to all p and varied by clinical severity p to p . Conclusions The SF-36 is a reliable valid and responsive measure of health-related quality of life and the FACIT-Fatigue is a brief and psychometrically sound measure of the effects of fatigue on patients with AS. These PROs may be useful .